Blisters

What are blisters?

Blisters are fluid-filled sacs on the outer layer of your skin. They form because of rubbing, heat, or diseases of the skin. They are most common on your hands and feet.

Other names for blisters are vesicles (usually for smaller blisters) and bulla (for larger blisters).

Blisters often happen when there is friction - rubbing or pressure - on one spot. For example, if your shoes don't fit quite right and they keep rubbing part of your foot. Or if you don't wear gloves when you rake leaves and the handle keeps rubbing against your hand. Other causes of blisters include:

• Burns
• Sunburn
• Frostbite
• Eczema
• Allergic reactions
• Poison ivy, oak, and sumac
• Autoimmune diseases such as pemphigus
• Epidermolysis bullosa, an illness that causes the skin to be fragile
• Viral infections such as varicella zoster (which causes chickenpox and shingles) and herpes simplex (which causes cold sores)
• Skin infections including impetigo

Blisters will usually heal on their own. The skin over the blister helps keep out infections. You can put a bandage on the blister to keep it clean. Make sure that there is no more rubbing or friction on the blister.

You should contact your health care provider if:

• The blister looks infected - if it is draining pus, or the area around the blister is red, swollen, warm, or very painful
• You have a fever
• You have several blisters, especially if you cannot figure out what is causing them
• You have health problems such as circulation problems or diabetes

Normally you don't want to drain a blister, because of the risk of infection. But if a blister is large, painful, or looks like it will pop on its own, you can drain the fluid.

There are some things you can do to prevent friction blisters:

• Make sure that your shoes fit properly
• Always wear socks with your shoes, and make sure that the socks fit well. You may want to wear socks that are acrylic or nylon, so they keep moisture away from your feet.
• Wear gloves or protective gear on your hands when you use any tools or sports equipment that cause friction.

Blood Clots

What is a blood clot?

A blood clot is a mass of blood that forms when platelets, proteins, and cells in the blood stick together. When you get hurt, your body forms a blood clot to stop the bleeding. After the bleeding stops and healing takes place, your body usually breaks down and removes the blood clot. But sometimes the blood clots form where they shouldn't, your body makes too many blood clots or abnormal blood clots, or the blood clots don't break down like they should. These blood clots can be dangerous and may cause other health problems.

Blood clots can form in, or travel to, the blood vessels in the limbs, lungs, brain, heart, and kidneys. The types of problems blood clots can cause will depend on where they are:

• Deep vein thrombosis (DVT) is a blood clot in a deep vein, usually in the lower leg, thigh, or pelvis. It can block a vein and cause damage to your leg.
• A pulmonary embolism (PE) can happen when a DVT breaks off and travels through the bloodstream to the lungs. A PE, especially if it is large, can damage your lungs and prevent your other organs from getting enough oxygen.
• Cerebral venous sinus thrombosis (CVST) is a rare blood clot in the venous sinuses in your brain. Normally the venous sinuses drain blood from your brain. CVST blocks the blood from draining and can cause a hemorrhagic stroke.
• Blood clots in other parts of the body can cause problems such as an ischemic stroke, a heart attack, kidney problems, kidney failure, and pregnancy-related problems.

Certain factors can raise your risk of developing blood clots:

• Atherosclerosis
• Atrial fibrillation
• Being overweight or having obesity
• Cancer and cancer treatments
• Certain genetic disorders
• Certain surgeries
• COVID-19
• Diabetes
• Family history of blood clots
• Overweight and obesity
• Pregnancy and giving birth
• Serious injuries
• Some medicines, including birth control pills
• Smoking
• Staying in one position for a long time, such as being in the hospital or taking a long car or plane ride

The symptoms for blood clots can be different, depending on where the blood clot is:

• In the abdomen: Abdominal pain, nausea and vomiting
• In an arm or leg: Sudden or gradual pain, swelling, tenderness, and warmth
• In the lungs: Shortness of breath, pain with deep breathing, rapid breathing, and increased heart rate
• In the brain: Trouble speaking, vision problems, seizures, weakness on one side of the body, and sudden severe headache
• In the heart: Chest pain, sweating, shortness of breath, and pain in the left arm

To find out if you have one or more blood clots, your health care provider:

• Will do a physical exam.
• Will take your medical history, which includes asking about your symptoms.
• May order blood tests, including a D-dimer test.
• May order imaging tests, such as
  • Ultrasound.
  • X-rays of the veins (venography) or blood vessels (angiography) that are taken after you get an injection of special dye. The dye shows up on the x-ray and allows the provider to see how the blood flows.
  • CT Scan.

Treatments for blood clots depend on where the blood clot is located and how severe it is. Treatments may include:

• Blood thinners.
• Other medicines, including thrombolytics. Thrombolytics are medicines that dissolve blood clots. They are usually used where the blood clots are severe.
• Surgery and other procedures to remove the blood clots

You may be able to help prevent blood clots by:

• Moving around as soon as possible after having been confined to your bed, such as after surgery, illness, or injury
• Getting up and moving around every few hours when you have to sit for long periods of time, for example if you are on a long flight or car trip
• Wearing compression stockings after surgery or during a long flight
• Regular physical activity
• Not smoking
• Staying at a healthy weight

Some people at high risk may need to take blood thinners to prevent blood clots.

Body Weight

Do you know if your current weight is healthy? "Underweight", "normal", "overweight", and "obese" are all labels for ranges of weight. Obese and overweight mean that your weight is greater than it should be for your health. Underweight means that it is lower than it should be for your health. Your healthy body weight depends on your sex and height. For children, it also depends on your age.

A sudden, unexpected change in weight can be a sign of a medical problem. Causes for sudden weight loss can include:

• Thyroid problems
• Cancer
• Infectious diseases
• Digestive diseases
• Certain medicines

Sudden weight gain can be due to medicines, thyroid problems, heart failure, and kidney disease.

Good nutrition and exercise can help in losing weight. Eating extra calories within a well-balanced diet and treating any underlying medical problems can help to add weight.

Bone Diseases

Your bones help you move, give you shape and support your body. They are living tissues that rebuild constantly throughout your life. During childhood and your teens, your body adds new bone faster than it removes old bone. After about age 20, you can lose bone faster than you make bone. To have strong bones when you are young, and to prevent bone loss when you are older, you need to get enough calcium, vitamin D, and exercise. You should also avoid smoking and drinking too much alcohol.

Bone diseases can make bones easy to break. Different kinds of bone problems include:

• Low bone density and osteoporosis, which make your bones weak and more likely to break
• Osteogenesis imperfecta makes your bones brittle
• Paget's disease of bone makes them weak
• Bones can also develop cancer and infections
• Other bone diseases, which are caused by poor nutrition, genetics, or problems with the rate of bone growth or rebuilding

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Bone Infections

Like other parts of the body, bones can get infected. The infections are usually bacterial, but can also be fungal. They may spread to the bone from nearby skin or muscles, or from another part of the body through the bloodstream. People who are at risk for bone infections include those with diabetes, poor circulation, or recent injury to the bone. You may also be at risk if you are having hemodialysis.

Symptoms of bone infections include:

• Pain in the infected area
• Chills and fever
• Swelling, warmth, and redness

A blood test or imaging test such as an x-ray can tell if you have a bone infection. Treatment includes antibiotics and often surgery.